[tube_ee]

Which is to say, why has nobody built a front-loading sixgun with the cylinder capacity and strength to shoot .44 Magnum-level smokeless-powder loads with modern bullets?

Simply a lack of market, or is there some technical reason that this would not work?

--Shannon

[The Janitor]

..And this is practical how?

[arcticap]

Well there's a .50 caliber ROA conversion:

http://www.gunblast.com/Cumpston_ClementsFugett.htm

http://www.gunblast.com/images/Cumpston_ClementsFugett/fiveshooter3.jpg

And the U.K.'s Westlake Engineering specializes in building smokeless single shot muzzle loading target pistols and revolver conversions up to .38 caliber:

http://westlakeengineering.com/4640/4694.html

http://westlakeengineering.com/mediac/400_0/media/DCP00258SHROUD~ON38.jpg

http://westlakeengineering.com/mediac/400_0/media/P1010013.jpg

http://westlakeengineering.com/mediac/400_0/media/Phoenix~RH~Side.jpg