243, 260 and 7-08 are all based on the 308 case. Changing from one to the other should be just as easy. AR10 platforms have simple conversions for each. 243 is a fine little round in a bolt gun for children and women due to it's sissykicker recoil, but the 260 and 7-08 are right on it's heels and throw 120-160gr projectiles which have better BC/SD, less wind drift and more knockdown power then any 243 load. Plus they are not as overbore so they won't be as hard on barrels. Ballisticly the only advantage the 243 holds is slinging tiny varmint bullets at 4k fps, not something that appeals to the assult rifle crowd usualy. A 123gr 260 can shoot evry bit as flat as a 185gr 300 win mag and drift slightly less.