Let's see, a CZ452 is a $400 or so rifle (per Buds Gun Shop) 10/22's are around $200... Yeah, the CZ had better outshoot the Ruger out of the box. Either is a good choice, just pick if you want a semi or bolt action.
People place value on different things. For some accuracy is the main priority and is what drives the purchase. For others, other qualities will factor into the purchase.
For example a lot of people spend over $1000 for a pre-64 Winchester 70 when an off the shelf $400 Savage will outshoot it.
I view the CZ 452 as something you could hand down to your kids...walnut and blued steel exude a bit more quality to me than an out of the box 10-22 with a syn stock or a cheap birch stock.
That being said you make some great points and I think the main thing the original poster needs to decide is whether he wants a bolt action or a semi.
The nice thing about .22LR rifles is that most are inexpensive enough that you can buy a few different types that will satisfy multiple desires.
I have a Remington 541S that is my favorite .22LR rifle to shoot but my Marlin 60 is fun as well. I will eventually get a 10-22 as well, and possibly a Savage MkII or CZ bolt action.
If I get rich someday I wouldn't mind a Cooper bolt action.
Lots of options out there that's for sure.