I carry a mouse gun. There. I said it.
I have an arsenal of mid and full size pistols and revolvers in .38, .357, 9mm, .40, and .45 as well as two drawers full of leather, kydex, pancake, IWB, OWB, and shoulder holsters.
I wear them and shoot them often...but I just can't do it every day. My work DOES require that my firearm is 100% invisible. I work with the public, and while I observe my right to keep and bare arms, I respect theirs to not be comfortable coming into a store with an obviously armed proprietor. I'm in business to make money, not try to educate the public on firearms.
I move a lot at work. I bend, I sit, I carry, I lift. Basically, a gun has to fit in my back pocket(s). This time of year I wear a sweat shirt or an untucked flannel. I'll strap a snub nose Ruger on my hip. I'll always pick a .357 snubbie over pocket pistol if given the choice. However, the pocket gun ALWAYS comes with me.
Most other times, I have to pocket carry only. This means an LCP or M&P Bodyguard (sometimes both) are what I carry on my person. I keep a full size in my office drawer. Day to day, 13-14 rounds of .380 carried on my person either via a gun and a reload or two firearms is adequate protection.
Now, I try not to be stupid. I had to run some material out to my other office yesterday. It's in a rougher part of town. I carried my M&P Bodyguard in my pocket like I always do...and had a 92fs in a shoulder holster. I know that we never know exactly when trouble is going to strike, but it is much more probable on that side of town.
I shoot a .380 pocket pistol well. I practice often. I ALWAYS have it on me. Even a single stack 9mm would get carried as much (by ME) as my little Mice.
I will say that I wish they would quite marketing these to inexperienced shooters or selling them to women who throw them in their purse and forget about them. They are snappy and take a lot of work to gain serious proficiency.