jag1954:
41 Mag and 45 Colt are among my favorite cartridges; hunt with, reload and actively shoot both...
Have a M25 for 45 - it has a great feel in my hand - load it primarily with 255 SWC or 265 LBT bullets at pressures in the high teen levels - not above 20k psi. A 255 gr SWC bullet at 1000-1050 fps is amazingly effective on game. Plus accurate, easy on gun, gunner and ears to shoot. Took the M25 on my walk about the back40 this afternoon, temp had not gotten up to zero - wind chill a lot below. When i got back, the gun frosted over right away in the basement - action still smooth. It is a so called classic M25, with MIM parts and hole - i know there are a lot of negative nancy comments about these attributes- this revolver felt great right out of the box, is tight, locks up great and shoots well - chambers throats are .451-.452; load mostly .452 cast bullets.
The 41 is a FA83, load it with 250 gr LBT bullets to approx 1220 fps, not max for 41 - but a good solid and highly effective load with great game penetration and LBT creates a good channel - and is highly "shootable". The FA is incredibly accurate and my sight set up is very quick for in brush shots. In my opinion, if one is serious about hunting with a handgun - a FA83 is a superior tool for this - it has been my primary deer/hog gun for over a dozen years. Depending upon your hand and 41 loads, M57 may/or not be optimally comfortable - i have shot one a few times - for me, hard to tell from the M25, except more recoil and blast. Either is a great choice.