Heavy hard Cast for me, always two holes and always a ton of blood. Usually there's less damage to the meat.
Whats nice is is you can shoot really mild loads if you want and they still pass all the way through. These mild loads make for really good accuracy from a 44. Good shot placement with any weapon is the key but a nice mild hardcast 44 blows a through like a good broadhead. 44 in a handgun is a fine combination for hunting, just right.