The arbor is threaded and lock pinned into the recoil shield. It ain't goin' no where without a stick of Dynamite or a zip disc cutter....
You can see the small end of the barrel wedge sticking out a little just below the rear of the ejector housing in your picture. The way to remove it is to use a hardwood or brass punch and tap it out. It'll come partway out the other side. At that point you can wiggle the barrel a little and pull forward at the same time and the barrel and ejector will slide or pop off depending on how clean or sticky the gun is. At that point the cylinder can slide forward off the arbor for cleaning.
When you put the cylinder and barrel back on resist the urge to hammer the wedge back in with a big mallet. They do just fine with a firm finger push or at most a light tap with a small block of hardwood such as maple.
Don't sweat the strength. They are fine with the sort of loads I suggested in my last post. A lot of us enjoy shooting the old Colt open top designs in both "proper" cap and ball black powder versions and the "Johnny come lately" conversions like yours
Just do NOT stick any hot loads such as a lot of folks would use from a Ruger for hunting into the gun. It's not made for that sort of stuff. Stick with cowboy action or moderate loads that peak at around 12K to 13K and the gun will last and endure in fine condition for YEARS to come.
And I can vouch that there is nothing "mouse fart" like about a 12 to 13K .45Colt load. Unless you're a Magnum recoil junky such loads will give your hand a solid but friendly kick to let you know you're shooting something quite serious.
Show this gun off in the Black Powder forum and the guys will chuckle to themselves at your concern before writing you a reply that says much the same as I've posted.
You're a very lucky sort of guy to have one of these. For some reason they charge a pretty premium price for them. They are often VERY nice shooters. As I said, Uberti makes a nice gun and the bore and muzzle recieve all the right sort of attention to ensure a very good level of accuracy for the gun.
You'll likely find that it shoots best with cast lead bullets. Something reasonably soft so it can obturate and bite into the rifling with the fairly low pressure levels. And if you don't already reload in .45 Colt then you sure want to start. Not many of us are willing to pay for factory ammo for anything that starts with a ".4" other than .40S&W. With reloading your own you can easily keep the cost down to around 20 cents a round. That's $10/50. Compare that to what factory .45Colt costs.
EDIT- Oops I see that you're still considering buying the gun. For some reason I jumped to the assumption that you already had it.