Not an engineer and certainly no expert but I would think an alloy frame M1911 in 10mm. wouldn't last very long. Don't believe it would be very pleasant to shoot either.
Why do you long for an aluminum frame? I would rather have a steel frame if I'm buying a metal gun regardless of caliber. Obviously aluminum will save some weight, but still.
Many manufacturers have a hard time getting steel 1911 frames to stand up to thousands of 10mm rounds. The 10mm is not in the same "power band" as a .45 ACP... it's significantly hotter.
There was a company making aftermarket aluminum Glock frames for a while. I don't know if they're still around. I heard that they didn't work very well because the Glock design required a little bit of frame flex to work properly.
Aluminum, even with scandium added, just doesn't have the strength to handle the recoil of a very powerful round. The LAST thing you want is the frame failing and the slide blowing back in your face.
My 10mm aluminum framed Commander has over 70,000 rounds of full power (210+ PF) ammunition through it with no meaningful wear. Weighs as much as a Glock 29 but all the benefits of the 1911 platform.
Even though you don't see any "meaningful wear" doesn't mean the frame won't crack and fail. When you step up to this kind of power level a steel frame is a really good idea. (and less recoil as well) I have seen a number of steel frame 1911s in .45 ACP and 10mm develop cracks from shooting major power loads. It may take a while but eventually the slide will beat the frame to death. If you beat on a piece of Al. it will become brittle. It is an amzing material but it does have limitations in some applications.
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