I own 1911s in both .45acp and 10mm, and I handload for both.
An alloy-framed, Commander-sized 1911 in .45 acp is a nice size and weight for carry or range use (~28 oz.) At that, you can get an alloy-frame in 3" size as well (24 oz.). In 10mm, you need a steel frame (36-38 oz.), which (for me) takes it out of EDC consideration. To clarify, I have done it, but my back protests these days.
Edited to add: I see that in your follow-up post, you mention CC use. So that may be something to consider. While my 10mm is a Commander-size, to get the most out of the 10mm, most recommend a 5" barrel. A full-size steel 1911 puts us up to 40-42 oz.; all quoted weights are empty. Some people carry a 5" steel 1911; if you wish to join them, more power to you. Just examine your options and do your homework before you commit.
You can find .45acp brass any and everywhere. Finding 10mm range brass is like finding a unicorn's sunglasses. Plan on buying new stuff from Starline or buying factory ammo and shooting it off for brass.
I own the 10mm because it is unique, it is fun, and because I can. It is an expensive and exotic toy. If I were to sell one tomorrow it would be the 10mm, without question.