Originally posted by Sgt. Dusk: It surely drops anybody with the shot in the head even from further distances
I don't know where you read or heard this, but there are many accounts of .22, .25, .32, and .380's.........and even the occasional 9mm........bullets glancing off a person's skull.
Yes, .22LR bullets will kill. But your goal in self defense is to S-T-O-P the attacker. And a .22 is a very poor tool against a determined attacker. Maybe he'll stop as soon as he sees you have a firearm. If so, great.....you stopped him.
But if he's determined, unless you have some sort of physical handicap or statute that prevents you from using a service caliber weapon, consider a .38 Special or bigger (in revolvers) and consider a 9mm or larger in semiautomatics. Even then, have a "Plan B." Because pretty much all handguns are weak.