I haven't seen any data on the 243, but would think it would benefit from a longer barrel more than most.
The 243 will lose 100 fps per inch below 22 inches (with 100 grain bullets)...
my apologies for trotting this link back out to those that have seen it, but i think this discussion warrants it - it is a link to some chrony data i did w/ a 243 in a 16.5" barrel and a 26" barrel: www.baitshopboyz.com/forum/forum_posts.asp?TID=18089&PN=3 if you read the link you'll note velocity per inch using same lot# factory ammo equates to around 35 f/s/inch between a 16.5" barrel and a 26" barrel depending on specifics.
probably a charlie sisk experiment. he did it w/ a number of chamberings. his thesis was that whatever velocity you lose you can mitigate by going w/ a faster or different powder combination. his findings were interesting, indeed, and especially relevant because it was the same barrel being used. however, the theory was somewhat of a myth, but it did work quite well in some examples.I don't have a link to the data results, but recently read of a gunwriter who took a 27" barreled 270 and cut 1" off the barrel at a time and measured velocity loss at each increment until he got to 21". There was a total of 114fps velocity loss. TOTAL.
to that end, i conducted an experiment of my own w/ an 8x57 mauser. starting w/ a 29" barrel and worked it down to 16" or so in various increments. my findings were that velocity loss in the 8x57 wasn't much, and i would say that was probably a function of the relatively low powder charge in relation to bore diameter (the custom 8x57 i had built sports a 17" barrel if that's any indicator). i have also run an experiment w/ a 7 rem mag from 26" to 21" and found there to be a pretty significant drop in velocity once you dropped to about 23" or shorter (the custom 7 rem mag that i should have back in a couple weeks is 26"). and as long as the subject is there... i also tried the david tubb abrasive bullet trick to see if it worked as advertised in increasing velocity and accuracy in the 8x57... it did not.
for whatever it is worth... i have done pretty extensive hand load work for both the 243 and 270 (i own examples of each), and neither is a cartridge i find particularly good in a short barrel. however, i still think a 270 is better than a 243 in any given non-varminter hunting rifle scenario. i also think the op would be very well served to go up in bore size and take a serious look at the 308 win or at least a 308 win based case larger than 257 cal (and i think the world of the 25 souper, but not in this application).