I guided antelope in the 1970's and was fortunate enough over many years to draw tags myself here in NV a number of times and hunt MT a couple. I've killed them with 243, 257 Roberts, 257 R AI, 257 Wby (one of my personal favorites), 270, 7 Mauser AI, 30-06, and 300 Wby.
My first at age 12 was with a Savage mdl 99 FW 243, and my last two with the 7X57AI, which is my personal favorite. When setting up my stepson and grandson for their hunts I got them 270s if that tells you anything. I found a steal of a deal in a Carson City gun shop for my grandson. It was an Husqvarna 640 98 FN Mauser270, topped with a Leupold VariXII 3-9X40 friction in Redfield SR two-piece mounts. He had the Pre-64 Win Mdl 70 243 I had given him years earlier, but as the FW's were never known for stellar accuracy, I wanted a rifle and round that was, and the Husqvarna didn't disappoint when loaded with 130gr Speer Hot Cores.
He shot his antelope and mulie that year with the 270. I had installed a Timney Sportsman trigger but made no other changes. The Timney shrunk his groups by 1/2 from those shot with the stock single stage Mauser trigger.
His dad got a tag two years later, and I gave him the 270 I brought along for a loaner when I was guiding for several seasons. It was one I put together when I was dirt poor, as opposed to now when I am desperately dirt poor. Always being a scrounger, I talked a gunsmith acquaintance out of a 270 take off barrel from an 03-A3 sporter his customer was re-barreling to 25-06, then still a wildcat. The barrel housed spiders for a couple years in my closet, until I stumbled across an 03-A3 barreled action with the 1944 ordnance re-build '06 barrel, collecting dust in a local pawn shop. It had been part of an estate buy, and it was cheap. I took it and the 270 barrel to Frank, the gunsmith, and asked him to crank it onto the action, bend the bolt and D&T the receiver. As luck would have it, Frank had a tang-split Bishop stock for a Springfield he had replaced with a new Bishop. It was a throw in for my job he did.
I stripped and re-finished the old stock, drilled a small hole at the end of the tang crack, epoxied it and bedded the action. In went a Timney Sportsman with safety, and on top went a B&L 3-9 Scopechief. It was no real beauty, but it shot pretty well with my 130gr handloads. That was my 270. I took a decent "goat" that fall with it and a couple of mule deer over time. My SIL has it and a cherry 80's vintage Mdl 70 FW 270 I gave him a few years ago. They were beautiful rifles. I gave a second one I had, also a 270, to a great friend in Libby MT who took care of a house I had up there and had to sell. I use a Husky 1640 Dlx 7X57 AI now, but that's another story.
Oh man! I've made a short story long. To the OP, shoot whatever your gun likes.
