I have carried my G43 in the pocket on occasion, but it is only doable with certain pants with big pockets, my LCP however will fit into any pocket of any pants I own and very nice and compact.
I've had a want for a S&W 642 for almost a decade but I have basically given up on it and as many times as I've stood at the gun counter eyeballing one, ready to slap down $375-$400 for one, I've always walked away with a "maybe later" attitude because I don't feel the snub .38spl fulfills any real need that I can't address with my. 380 because in terms of terminal ballistics I'm not really gaining a whole lot with the .38 and the 642 is among the smallest .38's you can buy but it's fatter and doesn't carry quite as well in the pocket and at least with the .380 I can carry a couple spare mags including the gun without any discomfort or printing whatsoever and I've carried it, drawn it, shot it enough to know my capabilities with it and it's reliable.
But if I had to pick between one or the other, I think the .380 would get the nod from me but it's almost a coin flip. I could just as easily choose a .38spl snub but I like the .380 because I can carry the gun (7rds) plus 12rds in 2 spare mags with ease. Carrying 19 rds of .38spl would not be quite as convenient or easy......