Well, it could be argued that there is no true wilderness anywhere near me, so, that I should simply abstain from posting a reply. SE Texas does have some very thick vegetation, in places, however, making it irrelevant how close one may be to a road. I occasionally travel to/through areas with no mobile phone/LTE communication. The main threats are feral dogs and feral hogs, plus, of course, feral upright bipeds. I do not go about cornering feral hogs, to provoke them to charge. So, the “best” poll reply is going to be based upon what I regularly carry, day-to-day, but, even that is not constant. I typically start the day with a J-Frame or SP101 in a pocket holster. The J-Frame is normally loaded with lead wadcutters. If leaving our small city, very far, which means going into or through Houston, Texas, I am likely to “up-gun” to a Glock G17, loaded with Speer Gold Dots. So, that will be my poll reply.
Until about a year ago, I would up-gun to a Ruger GP100, chambered ,357 Magnum, if traveling to or through rural areas, but, well, arthritis caught up with my trigger fingers, so, I stopped pulling most double-action triggers, except for my small-frame revolvers. So, I have been working with my single-action revolvers, to build proficiency. I may well settle upon a different bullet type, than JHP, in the near future, in a caliber other than .357, but, for now, “self-defense JHP” will do, for a poll reply.
If traveling to places where large mammals roam the earth, I would, of course, feel obligated to do the homework, for the specific area, in order to be well-equipped, and to run a statistically meaningful sample size of the relevant ammo, through the chosen weapon(s). I have already bought several boxes of such ammo, solid copper, expanding copper, hard-cast, and bonded-core jacketed, to start this testing, largely due to curiosity.