For factory ammo, I've always shot the 100 gr pill out of my 243 for most game and never lost one or had one go any real distance. All shots were 350 yd or less. The bullet sure did its job. And for my 06. 180 gr bullet has done the job on everything up to Moose with very similar results as the 243 ammo. No shots past 350 yds. Anyone find the same results.