I'd about have to bet that the most likely part to develop a crack would be in the slide...in the ejection port adjacent to the locking lug... from the extractor channel to the starboard side...and possibly
in the breechface from the firing pin hole to the extractor channel.
I've got 1911s with cracked frames that I check-drilled 25 years ago, and they haven't moved since. I guess I'll get around
to havin'em tigged up one day...
Maybe a 1911 with a ramped barrel would fit that bill, but I have seen such barrels throated so much to gain reliability that the case head support is almost where it was with the standard type barrel.