I chose .45ACP as my caliber of choice. I got my CCP the day after Thanksgiving in 2008 and tried various calibers but felt most comfortable with .45. I was on a budget that could barely afford a used Glock since my job ended in 2009. What I found was a LNIB Ruger P345 and we have been friends since then. My glove size is XL so I guess I have large hands and they are very comfortable with both DA and SA. I've shot 1911s but never fell in love with them and could only afford the lower end of the scale. I shoot Glocks well but they don't fit my hand like the Ruger. I recently got a Kahr DAO .45 and shoot it better than the Ruger at 7-15 yards.