The .22 mag rimfire makes sense as a hunting cartridge in rifles. For use in a pistol not so much except in revolvers with a spare .22 lr cylinder. One can use the the .22 mag shot loads for snakes. In semiauto 9mm is a better choice for me and but it might not be for you. 9mm fmj is not so much more expensive and is much more powerful. When they make a .22 mag auto loader with a reliable .22 LR conversion kit, I will interested.