I have a 2" 605. Not a target gun, never meant to be. Solid and reliable. Use 38+p in mine (357 is flashy and frightfully inefficient in short barrels) and would not feel underarmed unless I needed a rifle.
Agree that a 38's worth of grain-o-sand shot is NOT enough to reliably stop a large snake. Use the 38 solids or back it up with a Bond 410 with a half ounce of #4 shot (I do).
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