45LC from an S&W, SAA, Taurus or "Italian cowboy gun" is practically a different caliber from 45LC+P in a Ruger, Center Contender, Freedom Arms or Anaconda.
The former can be topped with the 357, with difficulty.
The latter can spank a 44Mag by a little bit...Cor-Bons are not the hottest 45LC+P available.