Is it generally better to have a suppressor dedicated to a particular rifle or pistol? If I got one, I'm sure I'd want to get a threaded barrel for my 9mm pistol. Is switching back and forth a problem? Is it advisable to get a general use suppressor? Maybe a 45 caliber one that would work from 45 down? Do they even work that way? As the difference in size gets greater, does effectiveness get worse? As with many things firearm related, would it be better to start with a 22 and move up from there? I don't have a suppressor ready 22 at the moment, but I am looking into a bolt action rifle for target use. One of my wish list items is a suppressed lever action rifle in 45 Colt. Nothing like a 300+ grain bullet to up the power when velocity stops below 1,100 fps. For practical and financial reasons, a 300 Blackout bolt action is more likely if I jump into this.