Sure, they cost more than a conventionally made safe of comparable quality and security. The design is unique, patented, and extremely practical on several levels.
Even the largest Zanotti model can be unloaded from the truck by two or three people of average strength, even in the absence of a lift gate. Try that with your 25-gun Browning, Ft Knox, or the like. As common carrier delivery contracts are almost always "to the curb", this is no small consideration. The driver will not help you get it off the truck, nor will he wait for you to assemble the manpower to do it. Same for getting it from the curb into your home - your problem.
You can negotiate with most local dealers for delivery, and sometimes even installation. Don't expect it to be cheap, and plan on paying a lot more if you want it anywhere but on the ground floor. If you entertain any fantasies of being able to get 800-odd lbs. of metal even to the other side of a room using appliance rollers or a dolly, give my regards to Santa and the Easter Bunny.
If you want or need to change your address, count on spending about 50% of what that safe cost you to have it moved if it weighs 350 lbs or more. Check it out; you'll be appalled.
When I factor-in the practical problems I avoided, such as getting a 25-gun unit off of the truck, into my house, and down a flight of stairs into my basement (not to mention what the professional help necessary to accomplish the above would've cost) I figure that my Zanotti was a bargain.