For me, I have to say the Colt Trooper MKIII that my mom bought for my dad after he got his first police job. It started a legacy of law enforcement and gun ownership in my family and still bears the holster wear of many years of use. There are at least three good stories I know associated with that gun, one about how my mom picked it out and bought it, another about how it aquired the non-stock grips that still adorn it's frame. I just about cry every time I think about that.
All that, and it is just a great looking gun. Tough, reliable, handles well. I find much beauty in that gun.