Sorry, I live in WI, and can't help you with anything carry related.
But I have one of the earlier Glock 21's without an accessory rail or finger grooves, and I like it just fine. It certainly is a rather massive beast, but even with my smallish hands and short fingers, (for a 6' tall guy at least...) I find the grip tolerable, especially considering it's a double stack .45 ACP.
If I were using it as a daily carry piece, I might consider getting the mod done where the hollow backstrap is shaved down and filled with solid polymer, but I seem to hang onto it OK as is. I think that it's more of a grip angle thing than an actual size issue as to why some don't like it. Heck, my wife's fingers alre all 1/4" longer than mine!
I had a few failures to cycle completely into battery on the last 3-4 rounds, but they were all limp-wristing related as I bought the Glock when I was still a newer shooter in the post-94 "gotta have a highcap!" panic. Presumably the heavy slide in relation to the lightweight frame, and near empty mag on the last few rounds was helping me limpwrist. I've had no issues once I figured it out it was my grip, and got used to other more beefy guns like my .357 mags.
I've been aware for some time dating way back to my usenet rec.guns days in the mid 90's about the "Glock Unsupported Chamber/KB! issue" at the feedramps in calibers other than 9mm. I've shot it with a wide range of cheap ball, to very hot Cor-Bon +p and have not seen any significant case bulging at the 6 o'clock feedramp position. My guess is that with proper ammo .40 and .45 Glocks are just fine, and the only risk from the agressive feed ramp leading a few millimeters into the chamber is that an overcharge is more likely to be a few percent more potent in a Glock. It's my suspicion that about 95% of the ammo that KB's in a Glock would KB most any other gun as well, with only a few surviving the overcharge as jsut an abnormally hot round.
My G21 used to be my nightstand gun for awhile, but I've traded that role for my HK USP 40. I'm just a tad more comfortable with the frame thumb safety, and DA first trigger pull if I leave the hammer down should I need to grab for it if wakened out of a sound sleep.
However, with the impending arrival of my twins, I may just go back to the Glock 21 as I've now gotten one of those quick-button electronic GunVault brand lockboxes, and if I'm awake enough to open the box, I can handle Glock trigger discipline, which I ought to display on all my guns anyway. I may also want to go back to the Glock as the simplicity of the Glock could make up a second or two lost to the electronic lockbox.
The only thing that could make me stick with the HK is that it was one of the first autos to pioneer the accessory rail, and mounting a light on it makes good sense for a house gun. If it's one of the newer 21's with the rail, unlike mine, that's moot. I haven't decided yet as I have a nice lithium/xenon flashlight, and being able to hold it away from your body, or illuminate items without pointing the pistol also has it's advantages.
