I have both of these revolvers. They are roughly the same size. The Ruger loaded weight is about three ounces less than the Charter and thinner at the cylinder making it a bit easier to carry. I shoot 125 grain "full house" loads in the LCR, and 200 grain Underwood .44 special full wadcutters in the Boomer. The felt recoil is about the same with both guns. My eyes have gotten old and for some reason, I can't really focus on the sights anymore, so I have reverted back to "point shooting" so the lack of sights on the Boomer is not an issue for me. I can put five rounds in a pie plate nailed to a tree up to 25 feet pretty fast and that is fine...for me. Any further than that, and I'll just throw the empty smoking gun in the general direction of the threat and run like hell. My question is about stopping power. When an attacker is high on meth and bath salts and running toward me wielding a machete, or just super pissed and intends to murder me, which round would be the most effective to stop the attack cold. Keeping in mind that the only way to achieve a "one shot stop" is a hit to the brain or spinal cord. I love the .357 round. Fired from the 2 inch barrel, I get velocities roughly equal to a 9mm fired from a four inch barrel at around 1150 fps with the 125 grainer. The .44 on the other hand, with the hard cast full wadcutter is running around 850 fps from the Charter. Penetration is not an issue with the .44 and over penetration is not a concern where I live. I really want to carry the Ruger, but will the .357 hollow point penetrate enough muscle and bone to take out a section of spine on a larger attacker from the 2 inch barrel? I realize that a spinal hit would require a bit of luck on a quickly moving target, but I know the .44 is up to that task. The .357 bullet will expand but will it penetrate deep enough to do the job? Which would you carry and why?