The Purdue Rifle/Pistol club has six, with at least a quarter million through each. All are at least 20 years old, probably more. Three of them are dead reliable with almost anything they're fed (they get sticky with Eley sport) one is kind of finicky, and the other two build up massive amounts of fouling at the bottom of the chamber that make them fail to extract constantly. I can't seem to get that fouling to go away no matter how much I clean. All six are still dead accurate, though. One even has a slightly bulged barrel (I have no idea how that could happen in a .22 with that much metal around the barrel) and still shoots dead on. Each one's trigger breaks at a crisp 2.5 pounds.
A couple weeks ago I got one out with the intention of shooting the black out of a B-33 NRA target - I shot 600-700 rounds in about an hour and never had a malfunction. It had probably seen another 500 before that since it's previous cleaning.
One more thing - they all seem to prefer Federal. Doesn't matter if its the cheap bricks or the boxes of expensive stuff, they eat it right up.
Honestly, if I were to buy a semi-auto .22 pistol for under $1000, the 41 would be the only thing I'd consider.
ETA - They are extraordinarily easy to field strip and clean, as well. Detail stripping to replace worn parts in the slide is very tricky, however. Or rather, reassembly after the detail stripping.
