I've used see through rings on a lever-action, and a .22.
They were both Marlins, and had nearly identical iron sights.
It was useful to be able to use the scope at distance, and still have the flexibility for ironsight short shots with the rifle.
They were also very useful in teaching my wife the differences in lining up shots using the irons, and the scopes, and back and forth. She got very good, very quickly. She appreciated them, but in the end chose a loopy 4x for her scout rifle.
What you are giving up is some cool points, and some clearance. It is a compromise, so realize that. Outside of the guidegun/brush shots/longshots, I see a lot of use for these where the desire to have a long range optic AND have the ability to do close fast work without it would be useful.