I believe the 44s from Uberti all have a 1:18" twist today and a .452 groove dia.
True, but it hasn't always been so. Those that decide they want a metallic cartridge conversion seldom know this, and so spend a considerable sum without checking the groove diameter and twist in the barrel on their particular revolver.
If one purchases a replica already made as a cartridge revolver they will be able to avoid the possible (but not certain) negative issues associated with converting a replica C&B model.