On average, quality control is higher with a Ruger New Vaquero than any other Ruger SA, period. At least in stuff made since 1973. Ruger first made the NewVaq in 2005 and they re-did how the guns were made...literally re-engineered the assembly line along with the gun. Quality control is VERY good with these babies.
Plus we're generally seeing Ruger quality control levels being on an "upswing" of late across all models. The new management is doing things right. At various times past Ruger QC levels would sometimes droop for a while, more than the usual complaints, etc. Never anything really ghastly like Charco (bleah) or old Taurus guns from before they did their own importing (avoid Taurii that have importer's marks!) but still.
Right now, quality control levels are really sweet at Ruger.
Fun fact: the Ruger NewVaq has a little-known cousin. The 50th Anniversary Blackhawk in 357Mag is built on the same size "mid frame" platform as the NewVaq but with adjustable sights, so it's basically Ruger's answer to the Colt New Frontier. Nice piece.
When chambered in 357, a Ruger mid-frame SA can handle near-unlimited diets of the hottest 357 ammo available. It is NOT weak. The cylinder is beefier than a GP100 or S&W L-frame. In 45LC the NewVaq has to be limited to the same loads that are rated for a late-model Colt SAA or it's various clones. So in this size gun, the 357s are actually more powerful (in terms of raw energy topping out around 800ft/lbs) than the 45LCs (peak around 550ft/lbs).
My NewVaq 357 is around SN5xxx, 2005 production and has been a dream. Zero complaints, and it's my daily CCW with modified sights, SuperBlackhawk lower-slung hammer, modified grips and a spring kit.