The 158gr fbi load is the best load, as it out-performs every other .38 load out there (as well as a number of .357 loads).
Some lighter j-frames (especially scadium/titanium etc) require jacketed bullets and only shoot reliably with 125gr loads. So I carried 125gr in my 340 and 342 pd's. Managable recoil, reliable performance. It wasn't the most powerful thing out there, but its all about trade offs. The guns weighed 10 ounces and I could carry them anywhere.
-David