Thanks again for all of the kind suggestions.
Armored Farmer, I have a Judge that I bought for fun. I haven't had a chance to practice with it enough to feel like I know how well the 410 shells will perform. It's the 3" magnum version. Next time I have a chance to visit my BiL's place out in the country I should give it a work out. The few times I shot 3" magnum buckshot shells were fun and impressive. That would pretty much solve the penetration problem.
My LCR is 38 special. It's fabulous. It's my cargo pants carry piece. However, for HD I prefer a steel revolver. They're easier to shoot, and weight isn't an issue if it's just sitting on the nightstand. LCR's are sure nice revolvers, though. The trigger is outstanding.
I'm not an SP101 fan. They just don't fit my hands well. I've owned three and still have two of them, but they're kinda "meh" to me. The 2.5" 9mm and 4.2" 327 would both be fine for SD, but I just don't like them a lot. One of them has a decent trigger for an SP101, but that's still not saying much.
Ugly Sauce, If I had a short-barreled six-shooter in a 40-something caliber, I would certainly consider it, with the right ammo. I have four short-barreled revolvers like that, but they're all five-shooters. My 6" or longer large-framed revolvers seem a bit awkward for indoors.
Right now I have the 3" k-frame on my nightstand because it happened to be sitting around while I tried different holsters for it. I'll open up the safe today and see if the 2" or 4" is a better fit for the exact spot I like to keep it. Everyone in my house is an adult who is careful with firearms, so I can leave them pretty much wherever I want.
This thread has revealed that I am lacking a short-barreled N-frame. I need to take care of that one of these days. A 40-caliber revolver is also on my wish list, pretty much just because I don't have one. I think I finally have a deal worked out for a 3" j-frame. It probably won't be on my HD list, but I've been wanting one for a while now.
I'll give this one a try, while I'm messing around today. It's only 5". Maybe the extra inch won't turn out to matter much.