I'm playing around with a new S&W 4506, amazingly my first traditional double action (a.k.a. DA/SA). I'm noticing it has the most unergonomic thumb safety/decocker possible. So, my question for those more DA/SA savvy: when you're drawing from a holster, do you thumb off the safety with the strong hand when establishing the grip, or do you thumb off the safety with the weak hand when establishing the support? And, if the former, can you also use a retention holster? I've been running dryfire practices both ways, and neither seems compelling.