I have absolutely no bias towards large calibers. My first deer rifle was a .222 Remington followed by a 6mm Remington, then a 220 Swift and my father for many years hunted with a .222 Remington Magnum. With these three I killed a couple dozen head of deer and hogs. I learned that with cartridges such as these, which would include the .223, there is little margin for error, and much deviation from broadside shots result in wounded game. I now typically use a .308 or .280 Remington, especially when ranges are liable to exceed 200 yds. And FYI, my 35 Whelen is used strictly for elk.
That sir is a cartridge, not a bullet.
Of the several dozen deer I've killed in over 40 years, the only one I lost was with a .22 caliber rifle when I attempted a rear quartering shot. Lesson learned. With more muscular game such hogs, penetration is even more critical.
Yes, and that is one of the many "ifs" that goes along with using ANY .22 caliber rifle for medium game; one needs to use a controlled expanding bullet. But even then due to their relatively light weight, penetration will still be lacking. Simple physics.
People are going to sling .22 caliber bullets at deer and hogs in perpetuity for the simple reasons discussed here; infatuation with a platform and cheap ammunition.
So go in peace, use whatever makes you happy, but remember that your love for a cartridge doesn't make it more effective.
Thanks for your service.
35W