CAUTION: The following post includes loading data beyond currently published maximums for this cartridge. USE AT YOUR OWN RISK. Neither the writer, The High Road, nor the staff of THR assume any liability for any damage or injury resulting from use of this information. I have an early 2000’s Uberti Regulator in .45 Colt with a 4.75” barrel. I am working up a powder charge using 255 grain lead semi wad cutter, Unique powder, Winchester WLP primers, and once fired Starline brass. I have never gone through this exercise before, so I will share my observations and hopefully obtain some guidance from those who know better than I (not a high bar). Lyman’s 49th reloading handbook gives 6.0 grains of Unique as a suggested starting charge, and 8.5 grains as a max charge. The overall cartridge length (AOL) is specified to be 1.575” and my single stage press is putting the out at 1.5745” +/- 0.0005”. I have read questionable sources indicating the Uberti is stronger than the Colt it cloned, and old data allows for 10 grains of Unique. I would like to work up to 10 grains and see what I learn.