GRD: Good question. A big part of reloading is matching the ammo to the specific weapon. (And there are plenty of folks here who know a lot more about reloading than me who will hopefully chime in.) However, there are a few generalities in reloading. For example, when the 1911 came out, there wasn't a whole lot of ammo to choose from. The ammo companies had to make ammo that was fairly similar in order to function in the gun. And the guns had to be fairly similar to function with the limited amount of ammo available. I suspect that even today, most basic, hardball ammo from the various manufacturers is fairly close in ballistics since manufacturers would want it to work in every brand of 1911. When you deviate from hardball into the realm of swc and Rhino-blasting hollow points, things become quite different and would need to be carefully matched to the firearm. The hardball load I listed has worked well in 1911's from various manufacturers, a Sig P220, a Ruger 345, and a Beretta 8045. That's not to say it would be absolutely the most accurate load on earth for each of those guns. Probably wouldn't be. But it is "accurate" and reliable and isn't so hot as to be dangerous to me or harmful to a firearm. I think most reloaders here would use a recommended load as a starting point - something to fiddle with until it was right for their particular gun.