Upon returning from Vietnam I went into law enforcement, part of our POST quals were at 50 yards. I qualified with M28/19/66 (over the years) shooting Remington 158gr SJHPs, 125s were several years away from being produced.
During this period of time a Trooper saved the life of another Trooper with a 100 yard shot across a parking lot, M28/4"/158gr SJHP. He and I later became friends and shooting buddies, often shooting our S&W service revolvers at paper plates at absurd distances.
Later, I worked with an officer who had worked felony squad from another state, his duty carry was a worked over M27/6" in a shoulder rig. I could hold my own past 100 yards with a worked over M66/ 4", but at long distances I shot his M27 better than my M66.
Living in a very rural area next to wilderness, I often carry a M686+/6" in a Bianchi shoulder rig during cooler months while wearing layered outer clothing. This carry has significant access advantages over hip carry while seated/driving and/or zipped/buttoned/snapped outer clothing.
Six inch barrels will also lengthen PBR (point blank range) because of increased MV. My 686+ is sighted in for 50 yards and its trigger is just as sweet as the M27 and M66 I wrote about above. Engage multiple targets, or rapid fire with the magnum and one will soon learn the advantages of smooth and light DA trigger pulls.
Six inch barrels are also advantageous when engaging a target(s) and there isn't enough time to use sights.
I've never put a worked over GP100 through its paces, so I can't comment on its pointability or trigger.
FWIW, last year I took out a coyote that changed direction and 'trotted' toward myself and GSD, guesstimated 75-80 yards and shot it with a Colt 1911 in 38 Super, distance turned out to be 95 yards.