If your indeed talking about the Nosler bullets having the cannalure, it is usually put there for use in factory loaded rounds in which a lot of them are crimped.
Take the same bullet from a box off the shelf of your LGS and they will be smooth sided.
I have shot up a ton of both in several calibers, those with and without the cannalure looking and weighing the same other than that. They will all drive into small groups using the same loads for that particular rifle.
I have some "Blems" with cannalures in which the manufacturer was not mentioned, but I also have the identical bullet from a listed manufacturer, these all shoot the same as well.