The more I think about this, the more it seems like the problem has to be AFTER the rotor.
Here's why: if all of the drops were either accurate or light, there could be a problem with bridging in the hopper, incomplete filling of the rotor, or incomplete dumping of the rotor.
This is not the case, as there are heavier than desired drops, usually right after light drops. The powder is hanging up in the PTX or the drop tube.
I do not see how too much powder (nearly a double charge in some examples) could ever drop into the rotor cavity!
All this talk about pistol rotors and micrometer inserts does not answer the question of how the OP sees 8.00 grains when the rotor was set to deliver 4.2 grains. 8.00 grains will not fit in a rotor cavity set for 4.2 grains no matter what combination of inserts there are!
Bob
As a check of the above, the average charge from the OP' 20 drops is 4.017 grains, slightly less overall than desired, but indicative, I think, that the light charges have some powder hanging up downstream of the rotor that then drops out on later cycles.