Everytime I read posts about people who complain about rimfire issues with respect to misfires, I end up wondering how the heck I'm missing out on all this. Maybe I'm just lucky.
In my life, I've fired untold thousands of .22, mostly LR and magnum. CCI, Winchester, Remington, and some Federal. Probably a few oddball brands, as well. I can't remember when the last time I had a misfire was.
In fact, I've not noticed any significant differences in incidents of misfires in any brand I've ever shot. Yeah, I've had an occasional misfire, but that's it.
I'm not saying complaints of misfires are false...just that this is such a rare event for me that it's never been a concern in my experience, regardless of the brand I've bought.
What I buy is based first on accuracy and reliability. After that, it's price. If it shoots straight and consistent, I'll sight my gun in on whatever is most cost effective and available and that's what I'll generally stick with.
And by reliability, I mean it goes "BANG!" when I pull the trigger and it cycles in my autoloader, if that's what I'm shooting it from. (Cycling obviously isn't a concern for bolt actions.)