I think the K22 may come out at or near the top for accuracy. I have a couple of S&W K frame .22's and they outshoot all my other .22s (especially the 8 3/8 17-4).
I too like the WFN bullets in my revolvers. I do not worry about overpenetration, however. The majority of bullets fired in LE shootings completely miss their targets, so overpenetration is not the greatest consideration. I have not seen the data on non-LE shootings, but I will wager a similar...
In no particular order:
S&W Model 625-3 .45 ACP
Colt Combat Commander .45 ACP
S&W Model 13-4 .357 Magnum
Colt Combat Elite .45 ACP
Glock Model 27 .40 S&W (too ugly to photograph)
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