My wife came with a Berreta .25 ACP, which she gave back to her dad after I bought he what she 'wanted'. After shooting a number of rental guns at an indoor range, she decided on a CZ-75B in 9mm. Many thousands of rounds later, she decided a revolver, like I had, was in order. I made her a 65LS by adding some wood stocks to a police trade-in 3" 65. Loaded with .38 +P 158gr LHPSWC, it was a great 'stopper' - and appropriate for indoor use, when needed. She wasn't as fond of it as other revolvers. I had a new 2" +P rated 10 - same load - she said okay, although she was still not as fond of it, although she liked it better than the 65. She couldn't duplicate the pinpoint accuracy she enjoyed with that CZ-75.
Everything changed a year or so back, she picked up my 5.5" SS .45 Colt Redhawk and shot it... and proclaimed it HER house gun. I loaded some 250gr GDHP's at ~850 fps from it - similar recoil/POI as the 255gr 850 fps plinkers she liked. It should do quite well as a bad guy greetor in our home. My side has my 2.5" .44 Special 5-shot, an Airweight 296. Her side has a real hogleg! The key is to give her a choice, just steer her clear of high speed Magnum rounds. Remember, you don't want to start a fire in your home - or kill a neighbor... watch the collateral damage capability.
Stainz