.45ACP, I've got a Ruger Camp Carbine (takes 1911 mags), a S&W Model 625, and a handful of 1911s. Yes, my household is pretty much .22LR and .45ACP, with a smattering of .380ACP.
My reloader only does .45ACP, but it puts together barely-penetrate-the-cardboard Bullseye loads to +P Bowling Pin...