All I know is from reading: Most folks use something like a .338. The main thing is a heavy bullet for deep penetration. Nilgai are thick-skinned and heavy-boned critters. Live weight is from 400 (cow) to 700 (bull) pounds, as a generality.
One article I read said there are somewhere toward 10,000 of them on the King Ranch. I've seen them from the Intracoastal Waterway, down in that country.
I've read that some guide services won't take you hunting for Nilgai with anything less than a .300WinMag. I'd say that'd be a pretty good reference point.
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