I have and love a Colt Detective Special. It has a rebounding hammer and is safe to carry with all chambers loaded. Unlike comparable S&Ws, it has six, not five chambers. It is not rated for +P, but +P is basically an advertising gimmick, anyway.
Having said that, my daily carry gun is a Kimber Custom Classic in .45 ACP. When everything goes to pot, that's the gun I want in my fist.