Back when I was a fulltime cop, fulltime gunsmith, and ammo mfg., I had several officers requesting that I build such a load for them. I had told them that the bullet would be keyholing before they knew it and that it was more of a novelity than a usable load. But I built the load for those that did not want to listen to reason. I tried to tell them all that this was a "myth load" and that either a soft cast SWCHP or a JHP was proven stoppers. But 4 officers were demanding that this was the load they wanted and insisted that they wanted them loaded for them. Can't say I didn't warn them...
One of my additional duties was the Sgt. in charge of the shooting investigation team for our PD, and one night we were called to the scene of an off duty officer involved shooting. Sure enough, there was one of the guys that I had made this load for and it was the round he used. Now the badguy was dead, but he took three rounds at less than 10 ft. The autopsy revealed that two rounds had penetrated under 2.5" into the torso badly disformed, and only one had in fact inflicted a mortal wound by striking a major artery thus causing the subject to bleed out before the medical troops arrived. The round that severed the artery entered keyholed and thus went deeper into the torso.
Our findings were that the incident was handled within the department guidelines and that the officer used every precaution to insure the safety of others in the incident. Internal Affairs was ok with the shooting, and the grand jury said it was a justifiable shooting. But, the officer said that he wished he had listened to me and had used the JHP's that I offered him in the first place. The other three officers that insisted on having the inverted HBWC loads promptly bought JHP loads.
That is my take on the loading of such a round. It is, in my opinion, something to avoid.
Wade