If you can afford the ammo it would take to "Wear Out" most any modern pistol, you've got more money than me. I have a Glock 35 with 30,000 + rds of .40 thru it, and about 8,000 rds of 9mm thru the LW conversion barrel in the 35. I'm on my 3rd recoil spring, replaced as PM, not due to a failure. I've had two broken trigger return springs, and one slide stop. All replaced in the field in a matter of minutes with only a punch. I carried a Glock 22 as a duty gun for years and shot it a lot. Kept the pistol when I retired, still shoot it from time to time. I'd be hard pressed to estimate the number of rounds thru it. Only routine PM required. No parts failures. I really like the .40, although I have more .45s and 9mms than .40s, I shoot the 40 about 60% of the time.
If you want a .40, jump in. Noting special to be concerned about.
str1