I have been able to get Hercules powder at estate sales. I have no idea how old they are, but they are in 1/2 pound tin cans. And I have shot that stuff up, including Bullseye, and they work great.
As for better powders. In a 44 magnum, 8.5 grains Unique with a 240 L will put a bullet out in my M629 at just 1000 fps. I have a very tight M629. If I want more power, a 240 L with 17.5 grains 2400 gives me 1200 fps. And if you want to copy Keith's famous load, 22.0 grains 2400 with a 240, you will be around 1350 fps.
I do not enjoy shooting magnums anymore. Too much recoil and noise.
Bullseye is an outstanding powder in cases like the 9mm, 38 Special, 45 ACP. You get great accuracy at moderate velocities. When you get into something like the magnums, it might be a bit "peaky" at maximum loads.