Was that 45 acp or LC?
As for +p 38 spcl., it doesn't get much better than Longshot IMO. I burn a lot of it in 38, 9mm, and .40, and it flat out takes care of business in those.
If in fact 45 lc is on the list, HS6 has been a real winner for me with that. It functions very well with every weight bullet. HS6 is also a great powder for +P 38 spcl., though I much prefer Longshot given the option.
GS