I loaded the cylinder on my Colt 2nd generation 1851 Navy some years ago, when I was living in northern Idaho. Not a humid area, but not a bone-dry one, either.
Anyway, I left the cylinder outdoors for about six months. It was exposed to sub-freezing temperature, then summer heat of 100 degrees or more.
The chambers were loaded with Goex FFFG black powder, a felt wad lubricated with Hodgdon Spit Ball, a .380-inch ball and no grease over the ball. The caps were squeezed into an elliptical shape and pressed onto the nipples. No sealant such as beeswax covered the caps.
In early fall, the revolver was fired. No problems; all chambers fired successfully and I didn't notice any lack of power from powder contamination.
Nor did I note any evidence of rust in the chambers.
Yes, a cap and ball revolver's cylinder may be left loaded for years, decades even. I don't suggest it, however.
Rust can begin in the chamber, since one of the ingredients of black powder is potassium nitrate, also known as saltpetre. This is a salt before and after combustion and will promote rust.
And yes, even stainless steel will rust given enough time and exposure.
About 25 years ago, I had a stainless steel Ruger Security Six that was left in the trunk of my 1973 Duster. The trunk leaked all winter, unknown to me, so that revolver sat in water for months.
When I pulled the revolver out, in the spring, it had a very faint layer of orange rust on one side. The rust wiped off, leaving an even fainter discoloration, but there is no doubt that the revolver rusted.
Stainless steel will rust, just takes a whole lot longer than carbon steel.
Another thing about cap and ball revolvers. The oversized ball forms a tight seal, but the cap has no such advantage. Moisture can work in between the cap and nipple over time, affecting or deadening the load.
The old-timers often worked beeswax or candle wax around the cap on the nipple, to make it somewhat waterproof. Wax was often placed over the ball as well, not for lubrication but for waterproofing.
Some years ago, I recall reading one Union officer who evaded capture by swimming to an island in a river. He found other Union soldiers hiding on the same island, waiting for nightfall to make their escape.
I recall him saying that he had waterproofed his revolver with wax over the balls and caps, and felt confident his revolver would fire. The other Union soldiers with sidearms had not done so, and they felt their revolvers were useless.
They later made their way back to Union lines. Curious, the officer fired his revolver and found that all loads fired perfectly. I don't recall if the others, who did not waterproof their loads, fired theirs.
Anyway, that's pretty effective waterproofing for a cap and ball sixgun to be immersed in water twice, then exposed to a wet holster for hours, and still fire.
I would not leave a cap and ball cylinder loaded for long. I think that with a carbon steel cylinder, rust is invited. Stainless steel may be more resistant but is not foolproof.
Even if the chambers do not rust, moisture can still deaden the load. Never underestimate the power of water.