Answers for CLB
I'm going to be reloading .45Colt, .380, and .32 S&W long.
Start with one. Learn the reloading basics. THEN branch out to other calibers. I reloaded .38/.357 for over a year before I started loading .45acp.
Don't confuse yourself or spead yourself too thin.
My suggestion is to start with the .45 Colt. There are more bullet weights available for it. Everything from 160gr up to twice that.
The "standard" .45 Colt load is a 250/255gr leasd bullet. Start with that.
Start with ONE particular bullet. Experiment with that one. (You'll really need 2 or 3 powders to really see what's best for you.) Then try the same weight in a different brand or style.
Then explore the 225/230gr bullets.
Then try the 200s.
Then try a 260 or 275.
Then move on to your .32.
And then your. 380. (With the .380 you'll have to chase brass.)
My Colt is not a Ruger so "cowboy" loads are needed
neeeent!
"Cowboy" loads are weak underpowered loads for role playing games, light target loads that actually don't have to be very accurate. Cowboy targets are rather large and close.
Your Colt is fully capable of firung REAL .45 Colt loads. Anything that isn't marked Ruger or Contender loads will be just fine. A modern Colt has a lot more strength than most people realize.
Would Unique fill all three needs...
Yes
but what would be optimum?
No
I want accuracy first and velocity second.
Unique can be a very accurate powder but no one single powder is the most accurate in every caliber with every bullet. If there was such a powder there wouldn't be much of a need for any of the rest.
I'm confused as to even what bullet weight to chose but I feel I want to use cast bullets.
You need to determine what you WANT to shoot so you can determine what you NEED to load. The two books I mentioned in my previous post will help you greatly.
Are gas checks necessary for any of these guns?
Unless you are shooting lead bullets at very high velocities then you probably won't need gas checks. You can only use gas checks on bullets that are designed for them. And bullets so designed don't work as well without them.
If you are buying bullets from a commercial manyfacturer they will come with them if they are designed for them.